What is the role of hepcidin in iron homeostasis in the context of anemia?

A It increases iron absorption from the gut
B It decreases iron absorption from the gut ✓
C It regulates iron recycling from macrophages
D It has no role in iron homeostasis

Explanation

Hepcidin is a hormone that decreases iron absorption from the gut and regulates iron recycling from macrophages, playing a crucial role in iron homeostasis and the pathogenesis of anemia.

Source

Harrison's Principles of Internal Medicine
Hematology Hematology: Anemia Hematology: Anemia Medium MEDICAL Confidence: high