What is the role of heparan sulfate proteoglycans in the regulation of hematopoiesis?

A They inhibit the proliferation of hematopoietic stem cells
B They enhance the homing of hematopoietic stem cells to the bone marrow
C They promote the differentiation of hematopoietic progenitor cells
D They regulate the release of growth factors from the bone marrow niche ✓

Explanation

Heparan sulfate proteoglycans play a crucial role in regulating the release of growth factors from the bone marrow niche, which in turn affects hematopoiesis.

Source

Research articles on hematopoiesis
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Hard MEDICAL Confidence: high