What is the role of darbepoetin alfa in the management of anemia in patients with chronic kidney disease?

A To stimulate erythropoiesis and increase red blood cell production ✓
B To reduce inflammation and oxidative stress
C To inhibit hepcidin and increase iron availability
D To decrease blood pressure and cardiovascular risk

Explanation

Darbepoetin alfa is a long-acting erythropoiesis-stimulating agent that stimulates erythropoiesis and increases red blood cell production, reducing the need for blood transfusions in patients with anemia related to chronic kidney disease.

Source

Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline
Hematology Hematology: Anemia Hematology: Anemia Hard MEDICAL Confidence: high