What is the purpose of using a 'two-stage' crossmatching technique in blood transfusion?

A To detect ABO incompatibility
B To detect non-ABO antibodies
C To reduce the risk of hemolysis ✓
D To increase the speed of crossmatching

Explanation

The two-stage crossmatching technique is used to reduce the risk of hemolysis by first detecting ABO incompatibility and then detecting non-ABO antibodies.

Source

Medical Laboratory Technology textbook
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Medium MEDICAL Confidence: high