What is the primary role of the hormone leptin in energy homeostasis?

A Stimulating appetite and increasing food intake
B Regulating glucose metabolism and insulin sensitivity
C Suppressing appetite and increasing energy expenditure ✓
D Modulating thyroid hormone production and metabolism

Explanation

Leptin is a hormone produced by adipose tissue that plays a crucial role in regulating energy balance by suppressing appetite and increasing energy expenditure.

Mnemonic

Leptin = Less eating, more energy 'lept' to burn

Source

Guyton and Hall Textbook of Medical Physiology
Metabolic and Nutritional Disorders Endocrinology Energy Homeostasis Medium MEDICAL Confidence: high