What is the primary role of the chemokine CXCL12 in hematopoiesis?
A
To promote the differentiation of progenitor cells into mature blood cells
B
To regulate the migration and homing of hematopoietic stem cells to the bone marrow
✓
C
To inhibit the proliferation of hematopoietic stem cells
D
To induce the apoptosis of mature blood cells
Explanation
CXCL12 is a chemokine that plays a crucial role in the migration and homing of hematopoietic stem cells to the bone marrow, where they can interact with the niche and undergo further development.
Hematology
Hematology: Hematopoiesis
Hematology: Hematopoiesis
Medium
MEDICAL
Confidence: high