What is the primary role of osteoblasts in the hematopoietic niche?

A To produce hematopoietic growth factors
B To regulate the calcium levels in the bone marrow
C To provide a scaffold for hematopoietic stem cell adhesion and retention ✓
D To phagocytose damaged or aged red blood cells

Explanation

Osteoblasts play a crucial role in the hematopoietic niche by providing a scaffold for hematopoietic stem cell adhesion and retention, thereby regulating their proliferation and differentiation.

Source

Blood journal
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Medium MEDICAL Confidence: high