What is the primary mechanism by which orlistat, a medication used to treat obesity, exerts its effects?

A Increasing the absorption of fat-soluble vitamins
B Inhibiting pancreatic lipase, thereby reducing fat absorption
C Stimulating the release of insulin, leading to increased glucose uptake
D Blocking the reabsorption of glucose in the kidneys
Orlistat works by inhibiting pancreatic lipase, an enzyme that breaks down triglycerides into fatty acids and glycerol, thereby reducing the absorption of fats.
National Institutes of Health
Metabolic and Nutritional Disorders Pharmacology Anti-obesity medications Medium MEDICAL Confidence: high