What is the primary mechanism by which anemia of chronic disease affects iron utilization in the body?

A Increased hepcidin production ✓
B Decreased erythropoietin production
C Increased transferrin receptor expression
D Decreased ferritin levels

Explanation

Anemia of chronic disease is characterized by increased hepcidin production, which leads to decreased iron absorption and utilization.

Source

Harrison's Principles of Internal Medicine
Hematology Hematology: Anemia Hematology: Anemia Medium MEDICAL Confidence: high