What is the primary function of von Willebrand factor in the coagulation pathway?

A To activate factor XII
B To bind and stabilize factor VIII ✓
C To inhibit the activity of protein C
D To promote the aggregation of platelets

Explanation

Von Willebrand factor plays a crucial role in the coagulation pathway by binding and stabilizing factor VIII, which is essential for the intrinsic pathway of coagulation.

Source

Harrison's Principles of Internal Medicine
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Medium MEDICAL Confidence: high