What is the primary function of the hematopoietic niche component, CXCL12?

A To promote the proliferation of hematopoietic stem cells
B To regulate the migration and homing of hematopoietic stem cells ✓
C To inhibit the differentiation of hematopoietic stem cells
D To induce the apoptosis of hematopoietic stem cells

Explanation

CXCL12, also known as stromal cell-derived factor 1 (SDF-1), is a chemokine that plays a crucial role in the regulation of hematopoietic stem cell migration and homing to the bone marrow niche.

Source

Blood journal
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Medium MEDICAL Confidence: high