What is the primary function of the glycoprotein, CD47, in red blood cells?
A
To facilitate the removal of aged red blood cells from circulation
B
To inhibit the phagocytosis of red blood cells by macrophages
✓
C
To regulate the expression of other cell surface proteins
D
To enhance the adhesion of red blood cells to endothelial cells
Explanation
CD47 is a glycoprotein that inhibits the phagocytosis of red blood cells by macrophages, thereby prolonging their lifespan in circulation.
Source
Blood journal, 2018;132(10):1025-1035
Hematology
Hematology: Blood Components
Hematology: Blood Components
Hard
MEDICAL
Confidence: high
