What is the primary cause of Lactic Acidosis in patients with uncontrolled Diabetes Mellitus?

A Impaired glucose uptake in cells
B Increased glucose production in the liver
C Enhanced anaerobic glycolysis ✓
D Defective insulin signaling pathway

Explanation

Lactic acidosis occurs when the body produces too much lactic acid, which can happen during intense exercise or in uncontrolled diabetes due to enhanced anaerobic glycolysis.

Source

Harrison's Principles of Internal Medicine
Metabolic and Nutritional Disorders Diabetes Mellitus Diabetic Complications Medium MEDICAL Confidence: high