What is the primary cause of lactic acidosis in patients with diabetic ketoacidosis?

A Insulin deficiency
B Glucagon excess
C Impaired lactate clearance
D Increased glycolysis
In diabetic ketoacidosis, the body's cells are unable to use glucose for energy due to a lack of insulin, leading to increased glucose levels in the blood. As a result, the body begins to break down fat for energy, producing ketones and increasing glycolysis, which can lead to lactic acidosis.
Harrison's Principles of Internal Medicine
Metabolic and Nutritional Disorders Metabolic Disorders Diabetic Ketoacidosis Hard MEDICAL Confidence: high