What is the primary cause of Lactic Acidosis, a condition characterized by the accumulation of lactic acid in the body?

A Diabetes Mellitus
B Mitochondrial dysfunction ✓
C Kidney disease
D Hepatic impairment

Explanation

Lactic Acidosis is primarily caused by mitochondrial dysfunction, which impairs the body's ability to utilize oxygen for energy production, leading to the accumulation of lactic acid.

Mnemonic

LAMBS - Lactic Acidosis Mitochondrial Backend Support

Source

Harrison's Principles of Internal Medicine
Metabolic and Nutritional Disorders Metabolic Disorders Lactic Acidosis Hard MEDICAL Confidence: high