What is the primary cause of anemia in patients with sideroblastic anemia?

A Defect in heme synthesis ✓
B Impaired iron absorption
C Increased hepcidin levels
D Mitochondrial dysfunction

Explanation

Sideroblastic anemia is characterized by the accumulation of iron in mitochondria, leading to impaired heme synthesis.

Source

Harrison's Principles of Internal Medicine
Hematology Hematology: Anemia Hematology: Anemia Hard MEDICAL Confidence: high