What is the name of the coagulation factor that is affected in patients with combined factor V and factor VIII deficiency?

A Factor X
B Factor V
C Factor VIII
D LMAN1 ✓

Explanation

LMAN1 is a gene that encodes a protein involved in the transport of factor V and factor VIII from the endoplasmic reticulum to the Golgi apparatus. Mutations in this gene can lead to combined factor V and factor VIII deficiency.

Source

Orphanet Journal of Rare Diseases
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: high