What is the mechanism by which hemoglobin's affinity for oxygen is regulated in response to changes in pH levels?

A Allosteric modulation
B Cooperative binding
C Buffering capacity
D Redox reaction
Hemoglobin's affinity for oxygen is regulated by allosteric modulation, which allows it to respond to changes in pH levels and facilitate oxygen transport.
Guyton and Hall Textbook of Medical Physiology
Hematology Hematology: Hemoglobin and Oxygen Transport Hematology: Hemoglobin and Oxygen Transport Medium MEDICAL Confidence: high