What is the mechanism by which activated protein C exerts its anticoagulant effect?

A Inhibition of factor VIIIa
B Inhibition of factor Va
C Activation of factor Xa
D Inhibition of thrombin
Activated protein C exerts its anticoagulant effect by inhibiting factor Va, which is a crucial component in the prothrombinase complex.
Robbins and Cotran Pathologic Basis of Disease
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: high