What is the function of the retinoic acid receptor alpha (RARα) in hematopoiesis?

A Regulation of granulopoiesis
B Maintenance of megakaryocyte development
C Promotion of monocytic differentiation
D Induction of promyelocytic leukemia cell differentiation ✓

Explanation

The retinoic acid receptor alpha (RARα) plays a crucial role in the induction of promyelocytic leukemia cell differentiation during hematopoiesis.

Source

Orkin et al. Hematopoiesis: A Developmental Approach
Hematology Hematology: Hematopoiesis Hematology: Hematopoiesis Hard MEDICAL Confidence: medium