What is the effect of a decrease in pH on the oxygen-binding properties of hemoglobin?

A It increases the affinity of hemoglobin for oxygen, reducing oxygen delivery to tissues
B It decreases the affinity of hemoglobin for oxygen, increasing oxygen delivery to tissues ✓
C It has no effect on the oxygen-binding properties of hemoglobin
D It increases the cooperativity of oxygen binding, but has no effect on overall oxygen delivery

Explanation

A decrease in pH (increase in acidity) reduces the affinity of hemoglobin for oxygen, facilitating its release to tissues and ensuring adequate oxygen delivery even in acidic environments.

Source

Berne and Levy Physiology
Hematology Hematology: Hemoglobin and Oxygen Transport Hematology: Hemoglobin and Oxygen Transport Easy MEDICAL Confidence: high