What is the difference between type 1 and type 2 von Willebrand disease in terms of von Willebrand factor levels and activity?

A Type 1 has decreased levels and activity, while type 2 has normal levels but decreased activity ✓
B Type 1 has normal levels but decreased activity, while type 2 has decreased levels and activity
C Type 1 has decreased levels but normal activity, while type 2 has normal levels and activity
D Type 1 has normal levels and activity, while type 2 has decreased levels and activity

Explanation

Type 1 von Willebrand disease is characterized by a quantitative deficiency of von Willebrand factor, resulting in decreased levels and activity. In contrast, type 2 von Willebrand disease is characterized by a qualitative deficiency, with normal levels but decreased activity of von Willebrand factor.

Source

Williams Hematology
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: high