How does the enzyme matrix metalloproteinase-9 contribute to the progression of atherosclerosis?

A It inhibits the formation of foam cells
B It promotes the degradation of extracellular matrix proteins ✓
C It stimulates the release of anti-inflammatory cytokines
D It breaks down low-density lipoprotein cholesterol

Explanation

Matrix metalloproteinase-9 is an enzyme that promotes the degradation of extracellular matrix proteins, leading to the progression of atherosclerosis by facilitating the migration of smooth muscle cells and the formation of plaque.

Source

Robbins and Cotran Pathologic Basis of Disease
Enzymes in Disease Pathophysiology Atherosclerosis Hard MEDICAL Confidence: high