How does the concentration of ATP and other organic phosphates affect the oxygen affinity of hemoglobin?

A ATP binds to hemoglobin and increases its oxygen affinity
B Organic phosphates bind to hemoglobin and decrease its oxygen affinity ✓
C ATP and organic phosphates have no effect on hemoglobin's oxygen affinity
D The effect of ATP and organic phosphates on hemoglobin's oxygen affinity is dependent on pH

Explanation

Organic phosphates, such as ATP and 2,3-bisphosphoglycerate, bind to hemoglobin and decrease its oxygen affinity, which facilitates the release of oxygen to tissues.

Source

Physiology textbooks
Hematology Hematology: Hemoglobin and Oxygen Transport Hematology: Hemoglobin and Oxygen Transport Hard MEDICAL Confidence: high