A patient with severe menorrhagia is diagnosed with a rare coagulation disorder known as Glanzmann thrombasthenia. What is the primary defect in this condition?

A Deficiency of platelet glycoprotein Ib
B Deficiency of platelet glycoprotein IIb/IIIa ✓
C Deficiency of von Willebrand factor
D Deficiency of fibrinogen

Explanation

Glanzmann thrombasthenia is a rare bleeding disorder characterized by a deficiency or dysfunction of platelet glycoprotein IIb/IIIa, which is essential for platelet aggregation and clot formation.

Source

Williams Hematology
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: high