A patient with hemophilia A is undergoing a major surgery. Which of the following is the most appropriate perioperative management strategy?
A
Administering recombinant factor VIII before and after surgery
✓
B
Using desmopressin to stimulate factor VIII release
C
Transfusing fresh frozen plasma to correct the coagulopathy
D
Administering vitamin K to enhance clotting factor synthesis
Explanation
Recombinant factor VIII replacement therapy is the mainstay of treatment for hemophilia A, especially in the perioperative period.
Source
National Hemophilia Foundation Guidelines
Hematology
Hematology: Coagulation Disorders
Hematology: Coagulation Disorders
Hard
MEDICAL
Confidence: high
