A patient with anemia is found to have an elevated level of soluble transferrin receptor (sTfR) in their serum. What does this finding most likely indicate?

A Iron deficiency anemia
B Anemia of chronic disease
C Erythropoietic activity and possible iron deficiency or hemolysis ✓
D Vitamin deficiency anemia

Explanation

An elevated level of soluble transferrin receptor (sTfR) is indicative of increased erythropoietic activity, which can be seen in conditions such as iron deficiency anemia or hemolysis. It reflects the body's attempt to increase red blood cell production.

Source

Blood Journal
Hematology Hematology: Anemia Hematology: Anemia Medium MEDICAL Confidence: high