A patient with anemia is found to have a normocytic anemia with a reticulocyte production index (RPI) of 1.5. What does this indicate?

A Inadequate erythropoietic response to anemia ✓
B Adequate erythropoietic response to anemia
C Increased destruction of red blood cells
D Decreased production of erythropoietin

Explanation

An RPI of 1.5 indicates that the bone marrow is not producing enough reticulocytes to compensate for the anemia, suggesting an inadequate erythropoietic response.

Source

Williams Hematology, 9th edition
Hematology Hematology: Anemia Hematology: Anemia Medium MEDICAL Confidence: high