A patient with anemia is found to have a low level of serum copper. What is the likely effect on their hematological profile?

A Decreased production of erythropoietin
B Impaired synthesis of hemoglobin due to decreased activity of ceruloplasmin ✓
C Increased risk of infection due to impaired neutrophil function
D Enhanced production of red blood cells due to increased availability of iron

Explanation

Ceruloplasmin, a copper-containing enzyme, plays a crucial role in the synthesis of hemoglobin. A deficiency in copper can lead to impaired activity of ceruloplasmin, resulting in decreased hemoglobin production and anemia.

Source

Harrison's Principles of Internal Medicine
Hematology Hematology: Anemia Hematology: Anemia Hard MEDICAL Confidence: medium