A patient with anemia is found to have a high level of soluble transferrin receptor (sTfR) in their serum. What does this indicate?

A Iron deficiency anemia
B Anemia of chronic disease
C Erythropoietic activity and possible iron deficiency ✓
D Hemolytic anemia

Explanation

Soluble transferrin receptor (sTfR) is a marker of erythropoietic activity and can be elevated in conditions where there is increased red blood cell production, such as iron deficiency anemia or hemolytic anemia.

Source

Blood Journal
Hematology Hematology: Anemia Hematology: Anemia Medium MEDICAL Confidence: high