A patient with a coagulation disorder is found to have a deficiency in factor XIII. What would be the expected clinical manifestation of this deficiency?

A Increased risk of venous thromboembolism
B Prolonged bleeding time due to impaired platelet function
C Impaired wound healing and recurrent spontaneous abortions ✓
D Enhanced fibrinolysis leading to bleeding complications

Explanation

Factor XIII stabilizes fibrin clots and its deficiency leads to impaired wound healing, recurrent spontaneous abortions, and possibly other complications related to unstable clot formation.

Source

Specialized hematology literature and case reports
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: medium