A patient presents with hypokalemia, which can lead to a condition known as hyperpolarization of the cell membrane. What is the effect of this condition on the excitability of neurons?

A Increased excitability
B Decreased excitability ✓
C No effect on excitability
D Variable effect on excitability

Explanation

Hyperpolarization of the cell membrane makes it more difficult for neurons to reach threshold potential, leading to decreased excitability.

Source

Berne and Levy Physiology
Electrolytes and Acid-Base Balance Physiology Neurophysiology Hard MEDICAL Confidence: high