A patient presents with easy bruising, petechiae, and a prolonged bleeding time, with laboratory results showing a significant decrease in factor XIII activity. What is the most likely diagnosis?

A Hemophilia A
B Von Willebrand disease
C Factor XIII deficiency ✓
D Disseminated intravascular coagulation

Explanation

Factor XIII deficiency is a rare bleeding disorder characterized by easy bruising, petechiae, and a prolonged bleeding time due to impaired clot stabilization.

Source

Williams Hematology
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: medium