A patient presents with easy bruising, petechiae, and a prolonged bleeding time. Laboratory tests reveal a normal platelet count but decreased platelet aggregation in response to collagen. Which of the following coagulation disorders is most likely?

A Bernard-Soulier syndrome
B Glanzmann thrombasthenia ✓
C Storage pool disease
D Scott syndrome

Explanation

Glanzmann thrombasthenia is a rare bleeding disorder characterized by impaired platelet aggregation due to defects in the glycoprotein IIb/IIIa complex, leading to easy bruising, petechiae, and a prolonged bleeding time.

Source

Williams Hematology
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: high