A patient presents with anemia, jaundice, and an elevated level of indirect bilirubin. What is the most likely diagnosis?

A Autoimmune hemolytic anemia
B Hereditary spherocytosis
C Glucose-6-phosphate dehydrogenase deficiency
D All of the above ✓

Explanation

All of the above options can present with anemia, jaundice, and an elevated level of indirect bilirubin due to hemolysis. Autoimmune hemolytic anemia is caused by autoantibodies against red blood cells, hereditary spherocytosis is a genetic disorder affecting the red blood cell membrane, and glucose-6-phosphate dehydrogenase deficiency is a genetic disorder affecting the enzyme that protects red blood cells from oxidative damage.

Source

Harrison's Principles of Internal Medicine
Hematology Hematology: Anemia Hematology: Anemia Medium MEDICAL Confidence: high