A patient is diagnosed with a condition characterized by an inability to form stable blood clots due to a deficiency in a specific glycoprotein that plays a critical role in platelet adhesion. Which of the following conditions is most likely responsible for this patient's symptoms?

A Bernard-Soulier syndrome ✓
B Glanzmann's thrombasthenia
C Gray platelet syndrome
D Thrombocytopenia with absent radius syndrome

Explanation

Bernard-Soulier syndrome is caused by a deficiency or dysfunction of the glycoprotein Ib-IX-V complex on platelets, leading to impaired platelet adhesion to von Willebrand factor and thus an inability to form stable blood clots.

Source

Clinical hematological literature and research studies
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: high