A patient is diagnosed with a coagulation disorder characterized by an autosomal dominant inheritance pattern and is found to have a mutation in the gene encoding for the von Willebrand factor. What is the most likely diagnosis?
Explanation
Von Willebrand disease type 1 is the most common form and typically exhibits an autosomal dominant pattern of inheritance. It results from a partial quantitative deficiency of von Willebrand factor.
Source
Medical genetics and hematology literature