A patient has a serum potassium level of 6.5 mEq/L. Which of the following is the most likely cause of this hyperkalemia?

A Cell lysis due to tumor breakdown
B Adrenal insufficiency
C Hyporeninemic hypoaldosteronism
D All of the above ✓

Explanation

All of the above options can cause hyperkalemia. Cell lysis due to tumor breakdown can release potassium ions into the bloodstream, adrenal insufficiency can lead to decreased aldosterone production which can cause hyperkalemia, and hyporeninemic hypoaldosteronism is a condition characterized by decreased renin and aldosterone production which can also cause hyperkalemia.

Source

Harrison's Principles of Internal Medicine
Electrolytes and Acid-Base Balance Pathophysiology Electrolyte Imbalances Hard MEDICAL Confidence: high