What is the clinical significance of detecting anti-K1 antibodies in a patient's serum?

A It can cause hemolytic disease of the newborn
B It can lead to an acute hemolytic transfusion reaction ✓
C It can indicate a previous transfusion reaction
D It can affect the interpretation of a direct antiglobulin test

Explanation

Anti-K1 antibodies can react with K1-positive red blood cells, leading to their destruction and potentially causing an acute hemolytic transfusion reaction.

Source

Medical Literature
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Medium MEDICAL Confidence: high