What is the role of the lectin pathway in the activation of the complement system during hemolytic transfusion reactions?

A It amplifies the classical pathway
B It initiates the alternative pathway
C It directly activates C3 convertase
D It recognizes and binds to foreign carbohydrates on transfused red blood cells ✓

Explanation

The lectin pathway is one of the three pathways that activate the complement system, and it plays a crucial role in recognizing and binding to foreign carbohydrates on transfused red blood cells, leading to the activation of the complement cascade and potentially causing hemolytic transfusion reactions.

Source

Immunochemistry and Immunobiology textbooks
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Hard MEDICAL Confidence: high