What is the significance of the Lewis blood group system in transfusion medicine, particularly in relation to the expression of Lea and Leb antigens?

A It determines the ABO blood group
B It influences the secretion of soluble ABO antigens ✓
C It affects the expression of Rh antigens
D It plays a role in the development of hemolytic disease of the newborn

Explanation

The Lewis blood group system is involved in the secretion of soluble ABO antigens and influences the expression of Lea and Leb antigens, which can impact transfusion medicine.

Source

Transfusion Medicine textbooks
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Medium MEDICAL Confidence: high