What is the role of CD47 in regulating erythrophagocytosis by macrophages?

A It inhibits the binding of red blood cells to macrophages, preventing erythrophagocytosis
B It enhances the recognition and engulfment of aged or damaged red blood cells by macrophages ✓
C It regulates the production of inflammatory cytokines during immune responses
D It modulates the expression of adhesion molecules on the surface of red blood cells

Explanation

CD47 is a protein that plays a role in regulating erythrophagocytosis by macrophages, facilitating the recognition and removal of aged or damaged red blood cells from circulation.

Source

Journal of Clinical Investigation
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Medium MEDICAL Confidence: medium