What is the role of the Rh null phenotype in the context of blood transfusion?

A Increased risk of hemolysis
B Reduced risk of alloimmunization
C Complete absence of Rh antigens ✓
D Presence of an additional Rh antigen

Explanation

The Rh null phenotype is characterized by the complete absence of Rh antigens on the surface of red blood cells, which can lead to complications in blood transfusion.

Source

American Association of Blood Banks
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Hard MEDICAL Confidence: high