Which of the following blood group antigens is known to be highly immunogenic and can cause severe hemolytic reactions, particularly in individuals with a history of previous transfusions or pregnancies?

A K1 antigen ✓
B Jk^a antigen
C Fy^a antigen
D S antigen

Explanation

The K1 antigen is highly immunogenic and can cause severe hemolytic reactions, particularly in individuals with a history of previous transfusions or pregnancies.

Source

Transfusion Medicine and Hemostasis
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Hard MEDICAL Confidence: high