What is the purpose of using albumin or low-ionic-strength saline in indirect antiglobulin testing?

A To enhance agglutination reaction
B To reduce the risk of hemolysis
C To increase the sensitivity of the test ✓
D To improve the specificity of the test

Explanation

Using albumin or low-ionic-strength saline in indirect antiglobulin testing increases the sensitivity of the test by enhancing the reaction between antibodies and red blood cells.

Source

Transfusion Medicine textbook
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Hard MEDICAL Confidence: medium