What is the role of the Kell blood group system in hemolytic disease of the newborn?

A It is responsible for the majority of HDN cases
B It can cause mild to moderate hemolysis
C It is a rare cause of HDN, but can cause severe hemolysis ✓
D It is not associated with HDN

Explanation

The Kell blood group system is a rare cause of hemolytic disease of the newborn, but can cause severe hemolysis due to the production of anti-Kell antibodies.

Source

American Association of Blood Banks
Hematology Hematology: Blood Grouping and Crossmatching Hematology: Blood Grouping and Crossmatching Hard MEDICAL Confidence: high