What is the mechanism by which heparin exerts its anticoagulant effect?

A By inhibiting the activity of thrombin
B By promoting the formation of plasminogen activator
C By binding to antithrombin III and enhancing its activity ✓
D By regulating the expression of coagulation factors

Explanation

Heparin exerts its anticoagulant effect by binding to antithrombin III (ATIII) and enhancing its activity, which leads to the inhibition of thrombin and other coagulation factors.

Source

Williams Hematology
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: high