Which protein is involved in the regulation of fibrinolysis, and its deficiency can lead to increased risk of thrombosis?

A Plasminogen Activator Inhibitor-1 (PAI-1) ✓
B Tissue Plasminogen Activator (tPA)
C Plasminogen
D Alpha-2 Antiplasmin

Explanation

Plasminogen Activator Inhibitor-1 (PAI-1) is a protein that regulates fibrinolysis by inhibiting the activity of tissue plasminogen activator (tPA), and its deficiency can lead to increased risk of thrombosis.

Source

Williams Hematology
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Medium MEDICAL Confidence: medium