What is the role of plasminogen activator inhibitor-1 in the fibrinolytic pathway?

A It activates plasminogen to form plasmin
B It inhibits the activity of plasmin
C It inhibits the activation of plasminogen to form plasmin ✓
D It has no role in the fibrinolytic pathway

Explanation

Plasminogen activator inhibitor-1 (PAI-1) is a protein that inhibits the activation of plasminogen to form plasmin, thereby regulating the fibrinolytic pathway.

Source

Guyton and Hall Textbook of Medical Physiology
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Medium MEDICAL Confidence: high