Which of the following coagulation disorders is characterized by an autosomal dominant inheritance pattern and is caused by a mutation in the SERPINC1 gene?

A Protein C deficiency
B Protein S deficiency
C Antithrombin deficiency ✓
D Factor V Leiden

Explanation

Antithrombin deficiency is a rare coagulation disorder that is inherited in an autosomal dominant pattern and is caused by mutations in the SERPINC1 gene.

Source

New England Journal of Medicine
Hematology Hematology: Coagulation Disorders Hematology: Coagulation Disorders Hard MEDICAL Confidence: medium